[Triumf-seminars] TRIUMF Special Seminar today at 13:00

[TRIUMF Seminars]

Date/Time: Tue 2021-03-23 at 13:00

Location:  Remote              

Speaker:   Sophia Pells (University of Manchester and the UK National Physical Laboratory)

Title:     Establishing production and quantitative imaging of theranostic terbium-155

Abstract: Nuclear medicine uses radioactive isotopes for diagnosis and treatment of disease. Many novel candidates have been identified in recent years.  Before any can be implemented clinically, reliable production routes, accurate nuclear data measurements, and metrology standards must be established. It is essential to calculate the radiation dose a patient has received following a treatment; this relies on quantitative imaging as imaging measurements must be related to a distribution of activity in the patient’s bo­dy. Therefore, suitable imaging parameters and corrections must also be determined.  

    Four radioisotopes of terbium have attracted interest as candidates for nuclear medicine: Tb-149 emits alpha particles suitable for therapy; Tb-152 emits positrons suitable for Positron Emission Tomography (PET); Tb-155 emits gamma-rays suited to Single-Photon Emission Computed Tomography (SPECT) and Tb-161 emits therapeutic beta and Auger electrons. As isotopes of the same element, their identical chemical properties mean they can be attached to the same pharmaceutical and will be processed indistinguishably in the body. For this reason, they form a theranostic set, and can be used for integrated therapy and diagnostic imaging permitting more personalised patient therapies.  

    This talk will discuss the process of establishing the traceability of novel medical isotopes. Focus will be on the diagnostic isotope Tb-155, from its production to the implementation of clinical quantitative imaging.  
oin Zoom Meeting
https://ca01web.zoom.us/j/64213531144

Meeting ID: 642 1353 1144
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Meeting ID: 642 1353 1144
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